BECN1 Antibody - C-terminal region
Artikelnummer:
ASB-ARP97177_P050
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| Artikelname: | BECN1 Antibody - C-terminal region |
| Artikelnummer: | ASB-ARP97177_P050 |
| Hersteller Artikelnummer: | ARP97177_P050 |
| Alternativnummer: | ASB-ARP97177_P050-25UL,ASB-ARP97177_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Mouse |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of mouse BECN1 |
| Alternative Synonym: | Atg, Atg6 |
| Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis including endosome formation in neuronal cells. May play a role in antiviral host defense (By similarity). |
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