BECN1 Antibody - C-terminal region
Catalog Number:
ASB-ARP97177_P050
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| Article Name: | BECN1 Antibody - C-terminal region |
| Biozol Catalog Number: | ASB-ARP97177_P050 |
| Supplier Catalog Number: | ARP97177_P050 |
| Alternative Catalog Number: | ASB-ARP97177_P050-25UL,ASB-ARP97177_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Mouse |
| Immunogen: | The immunogen is a synthetic peptide directed towards the C terminal region of mouse BECN1 |
| Alternative Names: | Atg, Atg6 |
| Plays a central role in autophagy. Acts as core subunit of different PI3K complex forms that mediate formation of phosphatidylinositol 3-phosphate and are believed to play a role in multiple membrane trafficking pathways: PI3KC3-C1 is involved in initiation of autophagosomes and PI3KC3-C2 in maturation of autophagosomes and endocytosis. Involved in regulation of degradative endocytic trafficking and required for the abcission step in cytokinesis, probably in the context of PI3KC3-C2 (By similarity). Essential for the formation of PI3KC3-C2 but not PI3KC3-C1 PI3K complex forms. Involved in endocytosis including endosome formation in neuronal cells. May play a role in antiviral host defense (By similarity). |
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