CASP1 Antibody - middle region

Produktübersicht

• Artikelname: CASP1 Antibody - middle region
• Artikelnummer: ASB-ARP97640_P050
• Hersteller Artikelnummer: ARP97640_P050
• Alternativnummer: ASB-ARP97640_P050-25UL,ASB-ARP97640_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Mouse
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of mouse CASP1
• Alternative Synonym: IC, ICE, Il1, Casp, Il1bc

Produktbeschreibung

Thiol protease that cleaves IL-1 beta between an Asp and an Ala, releasing the mature cytokine which is involved in a variety of inflammatory processes. Important for defense against pathogens. Cleaves and activates sterol regulatory element binding proteins (SREBPs). Can also promote apoptosis (By similarity). Upon inflammasome activation, during DNA virus infection but not RNA virus challenge, controls antiviral immunity through the cleavage of CGAS, rendering it inactive.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 44 kDa
• NCBI: 12362
• UniProt: P29452
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.