NTRK1 Antibody - middle region
Artikelnummer:
ASB-ARP97645_P050
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| Artikelname: | NTRK1 Antibody - middle region |
| Artikelnummer: | ASB-ARP97645_P050 |
| Hersteller Artikelnummer: | ARP97645_P050 |
| Alternativnummer: | ASB-ARP97645_P050-25UL,ASB-ARP97645_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human NTRK1 |
| Alternative Synonym: | MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA |
| This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date. |
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