NTRK1 Antibody - middle region

Product Overview

• Article Name: NTRK1 Antibody - middle region
• Biozol Catalog Number: ASB-ARP97645_P050
• Supplier Catalog Number: ARP97645_P050
• Alternative Catalog Number: ASB-ARP97645_P050-25UL,ASB-ARP97645_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human NTRK1
• Alternative Names: MTC, TRK, TRK1, TRKA, Trk-A, p140-TrkA

Product Description

This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 84 kDa
• NCBI: 4914
• UniProt: P04629-3
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.