RCC1 Antibody - N-terminal region

Produktübersicht

• Artikelname: RCC1 Antibody - N-terminal region
• Artikelnummer: ASB-ARP97721_P050
• Hersteller Artikelnummer: ARP97721_P050
• Alternativnummer: ASB-ARP97721_P050-25UL,ASB-ARP97721_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human RCC1
• Alternative Synonym: CHC1, RCC1-I, SNHG3-RCC1

Produktbeschreibung

Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 46 kDa
• NCBI: 1104
• UniProt: P18754
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.