RCC1 Antibody - N-terminal region
Catalog Number:
ASB-ARP97721_P050
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| Article Name: | RCC1 Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-ARP97721_P050 |
| Supplier Catalog Number: | ARP97721_P050 |
| Alternative Catalog Number: | ASB-ARP97721_P050-25UL,ASB-ARP97721_P050-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human RCC1 |
| Alternative Names: | CHC1, RCC1-I, SNHG3-RCC1 |
| Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP, and thereby plays an important role in RAN-mediated functions in nuclear import and mitosis. Contributes to the generation of high levels of chromosome-associated, GTP-bound RAN, which is important for mitotic spindle assembly and normal progress through mitosis. Via its role in maintaining high levels of GTP-bound RAN in the nucleus, contributes to the release of cargo proteins from importins after nuclear import. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. |
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