YWHAZ Polyclonal Antibody (Human)

Artikelnummer: ASB-ATP00015_T100
Artikelname: YWHAZ Polyclonal Antibody (Human)
Artikelnummer: ASB-ATP00015_T100
Hersteller Artikelnummer: ATP00015_T100
Alternativnummer: ASB-ATP00015_T100-100UL
Hersteller: Aviva
Kategorie: Proteine/Peptide
Applikation: ICC, WB
Spezies Reaktivität: Human
Immunogen: Recombinant Human YWHAZ aa 2-244
Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:14578935, PubMed:15071501, PubMed:15644438, PubMed:16376338, PubMed:16959763, PubMed:31024343, PubMed:9360956). Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (PubMed:35662396). Binding generally results in the modulation of the activity of the binding partner (PubMed:35662396). Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB (PubMed:35662396). Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation (PubMed:16959763). In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity).
Klonalität: Polyclonal
Konzentration: 1 mg/ml
Molekulargewicht: 28 kDa (245 aa)
NCBI: 7534
UniProt: P63104
Formulierung: PBS w/ 0.09% sodium azide