YWHAZ Polyclonal Antibody (Human)
Catalog Number:
ASB-ATP00015_T100
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| Article Name: | YWHAZ Polyclonal Antibody (Human) |
| Biozol Catalog Number: | ASB-ATP00015_T100 |
| Supplier Catalog Number: | ATP00015_T100 |
| Alternative Catalog Number: | ASB-ATP00015_T100-100UL |
| Manufacturer: | Aviva |
| Category: | Proteine/Peptide |
| Application: | ICC, WB |
| Species Reactivity: | Human |
| Immunogen: | Recombinant Human YWHAZ aa 2-244 |
| Adapter protein implicated in the regulation of a large spectrum of both general and specialized signaling pathways (PubMed:14578935, PubMed:15071501, PubMed:15644438, PubMed:16376338, PubMed:16959763, PubMed:31024343, PubMed:9360956). Binds to a large number of partners, usually by recognition of a phosphoserine or phosphothreonine motif (PubMed:35662396). Binding generally results in the modulation of the activity of the binding partner (PubMed:35662396). Promotes cytosolic retention and inactivation of TFEB transcription factor by binding to phosphorylated TFEB (PubMed:35662396). Induces ARHGEF7 activity on RAC1 as well as lamellipodia and membrane ruffle formation (PubMed:16959763). In neurons, regulates spine maturation through the modulation of ARHGEF7 activity (By similarity). |
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