TNFRSF11B Antibody - N-terminal region
Artikelnummer:
ASB-AVARP00033_T100
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| Artikelname: | TNFRSF11B Antibody - N-terminal region |
| Artikelnummer: | ASB-AVARP00033_T100 |
| Hersteller Artikelnummer: | AVARP00033_T100 |
| Alternativnummer: | ASB-AVARP00033_T100-25UL,ASB-AVARP00033_T100-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF11B |
| Alternative Synonym: | OPG, TR1, OCIF, PDB5 |
| TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. |
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