TNFRSF11B Antibody - N-terminal region
Catalog Number:
ASB-AVARP00033_T100
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| Article Name: | TNFRSF11B Antibody - N-terminal region |
| Biozol Catalog Number: | ASB-AVARP00033_T100 |
| Supplier Catalog Number: | AVARP00033_T100 |
| Alternative Catalog Number: | ASB-AVARP00033_T100-25UL,ASB-AVARP00033_T100-100UL |
| Manufacturer: | Aviva |
| Host: | Rabbit |
| Category: | Proteine/Peptide |
| Application: | WB |
| Species Reactivity: | Canine, Equine, Human, Mouse, Porcine, Rabbit, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the N terminal region of human TNFRSF11B |
| Alternative Names: | OPG, TR1, OCIF, PDB5 |
| TNFRSF11B is a member of the TNF-receptor superfamily. This protein is an osteoblast-secreted decoy receptor that functions as a negative regulator of bone resorption. This protein specifically binds to its ligand, osteoprotegerin ligand (TNFSF11/OPGL), both of which are key extracellular regulators of osteoclast development. Studies of the mouse counterpart also suggest this protein and its ligand play a role in lymph-node organogenesis and vascular calcification. Alternatively spliced transcript variants of this gene have been reported, but their full length nature has not been determined. |
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