FOXO4 Antibody - middle region
Artikelnummer:
ASB-AVARP01018_P050
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| Artikelname: | FOXO4 Antibody - middle region |
| Artikelnummer: | ASB-AVARP01018_P050 |
| Hersteller Artikelnummer: | AVARP01018_P050 |
| Alternativnummer: | ASB-AVARP01018_P050-25UL,ASB-AVARP01018_P050-100UL |
| Hersteller: | Aviva |
| Wirt: | Rabbit |
| Kategorie: | Proteine/Peptide |
| Applikation: | WB |
| Spezies Reaktivität: | Canine, Equine, Human, Mouse, Porcine, Rat |
| Immunogen: | The immunogen is a synthetic peptide directed towards the middle region of human FOXO4 |
| Alternative Synonym: | AFX, AFX1, MLLT7 |
| FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias. |
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