FOXO4 Antibody - middle region

Product Overview

• Article Name: FOXO4 Antibody - middle region
• Biozol Catalog Number: ASB-AVARP01018_P050
• Supplier Catalog Number: AVARP01018_P050
• Alternative Catalog Number: ASB-AVARP01018_P050-25UL,ASB-AVARP01018_P050-100UL
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: WB
• Species Reactivity: Canine, Equine, Human, Mouse, Porcine, Rat
• Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human FOXO4
• Alternative Names: AFX, AFX1, MLLT7

Product Description

FOXO4 is transcription factor involved in the regulation of the insulin signaling pathway. It binds to insulin-response elements (IREs) and can activate transcription of IGFBP1. The protein can down-regulate expression of HIF1A and suppress hypoxia-induced transcriptional activation of HIF1A-modulated genes. It is also involved in negative regulation of the cell cycle. A chromosomal aberration involving FOXO4 is found in acute leukemias.

Product Properties

• Clonality: Polyclonal
• Concentration: 0.5 mg/ml
• Molecular Weight: 54kDa
• NCBI: 4303
• UniProt: P98177
• Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.