CCND3 Antibody - C-terminal region

Produktübersicht

• Artikelname: CCND3 Antibody - C-terminal region
• Artikelnummer: ASB-AVARP03038_P050
• Hersteller Artikelnummer: AVARP03038_P050
• Alternativnummer: ASB-AVARP03038_P050-25UL,ASB-AVARP03038_P050-100UL
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: IHC, WB
• Spezies Reaktivität: Bovine, Canine, Guinea pig, Human, Mouse, Porcine, Rat, Sheep
• Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CCND3

Produktbeschreibung

CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 0.5 mg/ml
• Molekulargewicht: 33kDa
• NCBI: 896
• UniProt: P30281
• Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.

Bilder

Human Muscle

Rabbit Anti-CCND3 Antibody
Catalog Number: AVARP03038_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:600
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec

WB Suggested Anti-CCND3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateCCND3 is supported by BioGPS gene expression data to be expressed in Jurkat

Host: Mouse
Target Name: CCND3
Sample Tissue: Mouse Spleen
Antibody Dilution: 1ug/ml

CCND3 antibody - C-terminal region (AVARP03038_P050) in Human Jurkat using Western Blot