CCND3 Antibody - C-terminal region

Catalog Number: ASB-AVARP03038_P050
Article Name: CCND3 Antibody - C-terminal region
Biozol Catalog Number: ASB-AVARP03038_P050
Supplier Catalog Number: AVARP03038_P050
Alternative Catalog Number: ASB-AVARP03038_P050-25UL,ASB-AVARP03038_P050-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Proteine/Peptide
Application: IHC, WB
Species Reactivity: Bovine, Canine, Guinea pig, Human, Mouse, Porcine, Rat, Sheep
Immunogen: The immunogen is a synthetic peptide directed towards the C terminal region of human CCND3
CCND3 encodes a protein that belongs to the highly conserved cyclin family, whose members are characterized by a dramatic periodicity in protein abundance through the cell cycle. Cyclins function as regulators of CDK kinases. Different cyclins exhibit distinct expression and degradation patterns which contribute to the temporal coordination of each mitotic event. This cyclin forms a complex with and functions as a regulatory subunit of CDK4 or CDK6, whose activtiy is required for cell cycle G1/S transition. This protein has been shown to interact with and be involved in the phosphorylation of tumor suppressor protein Rb. The CDK4 activity associated with this cyclin was reported to be necessary for cell cycle progression through G2 phase into mitosis after UV radiation.
Clonality: Polyclonal
Concentration: 0.5 mg/ml
Molecular Weight: 33kDa
NCBI: 896
UniProt: P30281
Form: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Human Muscle
Rabbit Anti-CCND3 Antibody
Catalog Number: AVARP03038_P050
Formalin Fixed Paraffin Embedded Tissue: Human Lymph Node Tissue
Observed Staining: Cytoplasm
Primary Antibody Concentration: 1:600
Other Working Concentrations: N/A
Secondary Antibody: Donkey anti-Rabbit-Cy3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 - 2.0 sec
WB Suggested Anti-CCND3 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:62500
Positive Control: Jurkat cell lysateCCND3 is supported by BioGPS gene expression data to be expressed in Jurkat
Host: Mouse
Target Name: CCND3
Sample Tissue: Mouse Spleen
Antibody Dilution: 1ug/ml
CCND3 antibody - C-terminal region (AVARP03038_P050) in Human Jurkat using Western Blot