PROTEINASE 3 Antibody, IgG2b, Clone: [3B4], Mouse, Monoclonal

Produktübersicht

• Artikelname: PROTEINASE 3 Antibody, IgG2b, Clone: [3B4], Mouse, Monoclonal
• Artikelnummer: ASB-OAAD00317
• Hersteller Artikelnummer: OAAD00317
• Alternativnummer: ASB-OAAD00317-0.1ML
• Hersteller: Aviva
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
• Alternative Synonym: MBN, MBT, NP4, P29, PR3, ACPA, AGP7, NP-4, PR-3, CANCA, C-ANCA

Produktbeschreibung

Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes.
Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegeners granulomatosis.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [3B4]
• Molekulargewicht: 28kDa
• Isotyp: IgG2b
• NCBI: 5657
• UniProt: P24158