PROTEINASE 3 Antibody, IgG2b, Clone: [3B4], Mouse, Monoclonal

Product Overview

• Article Name: PROTEINASE 3 Antibody, IgG2b, Clone: [3B4], Mouse, Monoclonal
• Biozol Catalog Number: ASB-OAAD00317
• Supplier Catalog Number: OAAD00317
• Alternative Catalog Number: ASB-OAAD00317-0.1ML
• Manufacturer: Aviva
• Host: Mouse
• Category: Antikörper
• Application: WB
• Species Reactivity: Human
• Immunogen: Purified recombinant fragment of human Proteinase 3 expressed in E. Coli.
• Alternative Names: MBN, MBT, NP4, P29, PR3, ACPA, AGP7, NP-4, PR-3, CANCA, C-ANCA

Product Description

Proteinase 3, also known as PRTN3. PRTN3 is a serine protease enzyme expressed mainly in neutrophil granulocytes.
Its exact role in the function of the neutrophil is unknown but in human neutrophils proteinase 3 contributes to the proteolytic generation of antimicrobial peptides. It is also the epitope of anti-neutrophil cytoplasmic antibodies (ANCAs) of the cANCA (cytoplasmic subtype) class, a type of antibody frequently found in the disease Wegeners granulomatosis.

Product Properties

• Clonality: Monoclonal
• Clone Designation: [3B4]
• Molecular Weight: 28kDa
• Isotype: IgG2b
• NCBI: 5657
• UniProt: P24158