OCT4 Antibody, IgG1, Clone: [3A5], Mouse, Monoclonal

Produktübersicht

• Artikelname: OCT4 Antibody, IgG1, Clone: [3A5], Mouse, Monoclonal
• Artikelnummer: ASB-OAAD00322
• Hersteller Artikelnummer: OAAD00322
• Alternativnummer: ASB-OAAD00322-0.1ML
• Hersteller: Aviva
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: Purified recombinant fragment of OCT4 expressed in E. Coli.
• Alternative Synonym: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4

Produktbeschreibung

Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in protein-protein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation.
Oct4 is renowned as a transcription factor expressed by undifferentiated embryonic stem cells and embryonic germ cells.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [3A5]
• Molekulargewicht: 39kDa
• Isotyp: IgG1
• NCBI: 5460
• UniProt: Q01860