OCT4 Antibody, IgG1, Clone: [3A5], Mouse, Monoclonal
Catalog Number:
ASB-OAAD00322
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| Article Name: | OCT4 Antibody, IgG1, Clone: [3A5], Mouse, Monoclonal |
| Biozol Catalog Number: | ASB-OAAD00322 |
| Supplier Catalog Number: | OAAD00322 |
| Alternative Catalog Number: | ASB-OAAD00322-0.1ML |
| Manufacturer: | Aviva |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | WB |
| Species Reactivity: | Human |
| Immunogen: | Purified recombinant fragment of OCT4 expressed in E. Coli. |
| Alternative Names: | OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4 |
| Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in protein-protein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation. Oct4 is renowned as a transcription factor expressed by undifferentiated embryonic stem cells and embryonic germ cells. |
