OCT4 Antibody, IgG1, Clone: [3A5], Mouse, Monoclonal

Catalog Number: ASB-OAAD00322
Article Name: OCT4 Antibody, IgG1, Clone: [3A5], Mouse, Monoclonal
Biozol Catalog Number: ASB-OAAD00322
Supplier Catalog Number: OAAD00322
Alternative Catalog Number: ASB-OAAD00322-0.1ML
Manufacturer: Aviva
Host: Mouse
Category: Antikörper
Application: WB
Species Reactivity: Human
Immunogen: Purified recombinant fragment of OCT4 expressed in E. Coli.
Alternative Names: OCT3, OCT4, OTF3, OTF4, OTF-3, Oct-3, Oct-4
Members of Oct family of transcription factors specifically interact with Octamer motif ATGCAAAT, a regulatory element important for tissue- and cell-specific transcription as well as for transcription of a number of housekeeping genes. All of the members of the Oct family contain two highly conserved domains which are separated by 14-26 variable amino acids. These include the POU homeodomain and the POU-specific domain. Both are required for DNA binding and are involved in protein-protein interactions. Evidences indicate that regulation of Oct family transcription factors occurs at the level of phosphorylation.
Oct4 is renowned as a transcription factor expressed by undifferentiated embryonic stem cells and embryonic germ cells.
Clonality: Monoclonal
Clone Designation: [3A5]
Molecular Weight: 39kDa
Isotype: IgG1
NCBI: 5460
UniProt: Q01860