HDAC4 Antibody, IgG1, Clone: [7B2], Mouse, Monoclonal

Produktübersicht

• Artikelname: HDAC4 Antibody, IgG1, Clone: [7B2], Mouse, Monoclonal
• Artikelnummer: ASB-OAAD00335
• Hersteller Artikelnummer: OAAD00335
• Alternativnummer: ASB-OAAD00335-0.1ML
• Hersteller: Aviva
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: WB
• Spezies Reaktivität: Human
• Immunogen: Purified recombinant fragment of human HDAC4 expressed in E. Coli.
• Alternative Synonym: HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A

Produktbeschreibung

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.

Produkteigenschaften

• Klonalität: Monoclonal
• Klon-Bezeichnung: [7B2]
• Molekulargewicht: 119kDa
• Isotyp: IgG1
• NCBI: 9759
• UniProt: P56524