HDAC4 Antibody, IgG1, Clone: [7B2], Mouse, Monoclonal

Catalog Number: ASB-OAAD00335
Article Name: HDAC4 Antibody, IgG1, Clone: [7B2], Mouse, Monoclonal
Biozol Catalog Number: ASB-OAAD00335
Supplier Catalog Number: OAAD00335
Alternative Catalog Number: ASB-OAAD00335-0.1ML
Manufacturer: Aviva
Host: Mouse
Category: Antikörper
Application: WB
Species Reactivity: Human
Immunogen: Purified recombinant fragment of human HDAC4 expressed in E. Coli.
Alternative Names: HD4, AHO3, BDMR, HDACA, HA6116, HDAC-4, HDAC-A
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3.
Clonality: Monoclonal
Clone Designation: [7B2]
Molecular Weight: 119kDa
Isotype: IgG1
NCBI: 9759
UniProt: P56524