SNCG (BREAST CANCER-SPECIFIC PROTEIN 1) Antibody, IgG1, Clone: [1H10D2], Mouse, Monoclonal

Produktübersicht

• Artikelname: SNCG (BREAST CANCER-SPECIFIC PROTEIN 1) Antibody, IgG1, Clone: [1H10D2], Mouse, Monoclonal
• Artikelnummer: ASB-OAAD00427
• Hersteller Artikelnummer: OAAD00427
• Alternativnummer: ASB-OAAD00427-0.1MG
• Hersteller: Aviva
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human
• Immunogen: Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3)
• Alternative Synonym: SR, BCSG1

Produktbeschreibung

SNCG(also designated gamma-synuclein or breast cancer-specific protein 1), with 127-amino acid protein(about 14kDa), belongs to the synuclein fam- ily, which also includes alpha- and beta- synuclein.
Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, includ- ing liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 1 mg/ml
• Klon-Bezeichnung: [1H10D2]
• Isotyp: IgG1
• NCBI: 6623
• UniProt: O76070
• Formulierung: Liquid