SNCG (BREAST CANCER-SPECIFIC PROTEIN 1) Antibody, IgG1, Clone: [1H10D2], Mouse, Monoclonal
Catalog Number:
ASB-OAAD00427
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| Article Name: | SNCG (BREAST CANCER-SPECIFIC PROTEIN 1) Antibody, IgG1, Clone: [1H10D2], Mouse, Monoclonal |
| Biozol Catalog Number: | ASB-OAAD00427 |
| Supplier Catalog Number: | OAAD00427 |
| Alternative Catalog Number: | ASB-OAAD00427-0.1MG |
| Manufacturer: | Aviva |
| Host: | Mouse |
| Category: | Antikörper |
| Application: | IHC-Fr, IHC-P, WB |
| Species Reactivity: | Human |
| Immunogen: | Ni-NTA purified truncated recombinant SNCG expressed in E. Coli strain BL21 (DE3) |
| Alternative Names: | SR, BCSG1 |
| SNCG(also designated gamma-synuclein or breast cancer-specific protein 1), with 127-amino acid protein(about 14kDa), belongs to the synuclein fam- ily, which also includes alpha- and beta- synuclein. Three synucleins are located in the neuronal cytosol and enriched in presynaptic terminals, while SNCG is also expressed in many other non-neuronal tissues. SNCG is abnormally expressed in a high percentage of tumor tissues of diversified cancer types, includ- ing liver, esophagus, colon, gastric, lung, prostate, cervical, and breast cancer, but rarely expressed in tumor-matched nonneoplastic adjacent tissues. High levels of SNCG have been identified in advanced breast carcinomas suggesting a correlation between overexpression of SNCG and breast tumor development. |
