Anti-CD20 Monoclonal Antibody, IgG2a, Clone: [C273], Mouse
Artikelnummer:
ASB-OAAI00042
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| Artikelname: | Anti-CD20 Monoclonal Antibody, IgG2a, Clone: [C273], Mouse |
| Artikelnummer: | ASB-OAAI00042 |
| Hersteller Artikelnummer: | OAAI00042 |
| Alternativnummer: | ASB-OAAI00042-100UG |
| Hersteller: | Aviva |
| Wirt: | Mouse |
| Kategorie: | Antikörper |
| Applikation: | ELISA, FC, IHC, IP, WB |
| Spezies Reaktivität: | Human |
| Immunogen: | A synthetic peptide corresponding to C-terminus of human CD20 protein. |
| Alternative Synonym: | B1,B-lymphocyte antigen CD20,B-lymphocyte cell-surface antigen B1,Bp35,CD20,CD20 antigen,CD20 receptor,CVID5,FMC7,LEU-16,leukocyte surface antigen Leu-16,membrane-spanning 4-domains, subfamily A, member 1,S7. |
| CD20, a non-glycosylated protein, belongs to a member of the membrane-spanning 4A gene family. The molecular weight is at a range of ~34-37kDa depending on the degree of the protein phosphorylation. The CD20 antigen is present on Human pre B lymphocytes and B lymphocytes at all stages of matuRation. Thus, it plays an important role in the development and differentiation of B-cells into plasma cells. Low level of CD20 expression appears on normal T lymphocytes. Combination of chemo and Humanized CD20 antibodies has been reported in clinical study of lymphoma diseases. |
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