A synthetic peptide corresponding to C-terminus of human CD20 protein.
Alternative Names:
B1,B-lymphocyte antigen CD20,B-lymphocyte cell-surface antigen B1,Bp35,CD20,CD20 antigen,CD20 receptor,CVID5,FMC7,LEU-16,leukocyte surface antigen Leu-16,membrane-spanning 4-domains, subfamily A, member 1,S7.
CD20, a non-glycosylated protein, belongs to a member of the membrane-spanning 4A gene family. The molecular weight is at a range of ~34-37kDa depending on the degree of the protein phosphorylation. The CD20 antigen is present on Human pre B lymphocytes and B lymphocytes at all stages of matuRation. Thus, it plays an important role in the development and differentiation of B-cells into plasma cells. Low level of CD20 expression appears on normal T lymphocytes. Combination of chemo and Humanized CD20 antibodies has been reported in clinical study of lymphoma diseases.