CD33 Antibody (OABF00903-100UL), Unconjugated, Rabbit, Polyclonal

Artikelnummer: ASB-OABF00903
Artikelname: CD33 Antibody (OABF00903-100UL), Unconjugated, Rabbit, Polyclonal
Artikelnummer: ASB-OABF00903
Hersteller Artikelnummer: OABF00903
Alternativnummer: ASB-OABF00903-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, FC, ICC, IF, IHC-Fr, IHC-P, WB
Spezies Reaktivität: Human
Immunogen: KLH conjugated synthetic peptide derived from human CD33
Konjugation: Unconjugated
Alternative Synonym: CD33 antigen (gp67),CD33 molecule transcript,gp67,myeloid cell surface antigen CD33,p67,sialic acid-binding Ig-like lectin 3,SIGLEC3,SIGLEC-3.
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Klonalität: Polyclonal
Konzentration: 1 ug/ul
NCBI: 945
Formulierung: Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.