CD33 Antibody (OABF00903-100UL), Unconjugated, Rabbit, Polyclonal

Catalog Number: ASB-OABF00903
Article Name: CD33 Antibody (OABF00903-100UL), Unconjugated, Rabbit, Polyclonal
Biozol Catalog Number: ASB-OABF00903
Supplier Catalog Number: OABF00903
Alternative Catalog Number: ASB-OABF00903-100UL
Manufacturer: Aviva
Host: Rabbit
Category: Antikörper
Application: ELISA, FC, ICC, IF, IHC-Fr, IHC-P, WB
Species Reactivity: Human
Immunogen: KLH conjugated synthetic peptide derived from human CD33
Conjugation: Unconjugated
Alternative Names: CD33 antigen (gp67),CD33 molecule transcript,gp67,myeloid cell surface antigen CD33,p67,sialic acid-binding Ig-like lectin 3,SIGLEC3,SIGLEC-3.
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Clonality: Polyclonal
Concentration: 1 ug/ul
NCBI: 945
Form: Liquid. Aqueous buffered solution containing 100ug/ml BSA, 50% glycerol and 0.09% sodium azide.