TNFRSF10A Antibody

Produktübersicht

• Artikelname: TNFRSF10A Antibody
• Artikelnummer: ASB-OAPB00022
• Hersteller Artikelnummer: OAPB00022
• Alternativnummer: ASB-OAPB00022-0.1MG
• Hersteller: Aviva
• Wirt: Rabbit
• Kategorie: Proteine/Peptide
• Applikation: ELISA, ICC, IF, IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Immunogen: Anti-DR4 antibody (1139) was raised against a peptide corresponding to 19 amino acids near the carboxy terminus of human DR4. The immunogen is located within the last 50 amino acids of DR4.
• Konjugation: Unconjugated
• Alternative Synonym: APO2,CD261,cytotoxic TRAIL receptor,death receptor 4,DR4,TNF-related apoptosis-inducing ligand receptor 1,TRAIL receptor 1,TRAILR1,TRAILR-1,TRAIL-R1,tumor necrosis factor receptor superfamily member 10A,tumor necrosis factor receptor superfamily member 10a variant 2,tumor necrosis factor receptor superfamily, member 10a.

Produktbeschreibung

Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1 mg/ml
• Molekulargewicht: Predicted: 50kD Observed: 55kD (Post-modification: 1 N-linked glycosylation)
• NCBI: 8797
• Formulierung: Liquid. DR4 Antibody is supplied in PBS containing 0.02% sodium azide.