TNFRSF10A Antibody

Product Overview

• Article Name: TNFRSF10A Antibody
• Biozol Catalog Number: ASB-OAPB00022
• Supplier Catalog Number: OAPB00022
• Alternative Catalog Number: ASB-OAPB00022-0.1MG
• Manufacturer: Aviva
• Host: Rabbit
• Category: Proteine/Peptide
• Application: ELISA, ICC, IF, IHC-P, WB
• Species Reactivity: Human, Mouse, Rat
• Immunogen: Anti-DR4 antibody (1139) was raised against a peptide corresponding to 19 amino acids near the carboxy terminus of human DR4. The immunogen is located within the last 50 amino acids of DR4.
• Conjugation: Unconjugated
• Alternative Names: APO2,CD261,cytotoxic TRAIL receptor,death receptor 4,DR4,TNF-related apoptosis-inducing ligand receptor 1,TRAIL receptor 1,TRAILR1,TRAILR-1,TRAIL-R1,tumor necrosis factor receptor superfamily member 10A,tumor necrosis factor receptor superfamily member 10a variant 2,tumor necrosis factor receptor superfamily, member 10a.

Product Description

Receptor for the cytotoxic ligand TNFSF10/TRAIL (PubMed:26457518). The adapter molecule FADD recruits caspase-8 to the activated receptor. The resulting death-inducing signaling complex (DISC) performs caspase-8 proteolytic activation which initiates the subsequent cascade of caspases (aspartate-specific cysteine proteases) mediating apoptosis. Promotes the activation of NF-kappa-B.

Product Properties

• Clonality: Polyclonal
• Concentration: 1 mg/ml
• Molecular Weight: Predicted: 50kD Observed: 55kD (Post-modification: 1 N-linked glycosylation)
• NCBI: 8797
• Form: Liquid. DR4 Antibody is supplied in PBS containing 0.02% sodium azide.