CYP3A4 Recombinant Protein, E. coli

Produktübersicht

• Artikelname: CYP3A4 Recombinant Protein, E. coli
• Artikelnummer: ASB-OPCD02620
• Hersteller Artikelnummer: OPCD02620
• Alternativnummer: ASB-OPCD02620-10UG, ASB-OPCD02620-200UG, ASB-OPCD02620-50UG
• Hersteller: Aviva
• Wirt: E. coli
• Kategorie: Proteine/Peptide
• Applikation: Control, WB
• Spezies Reaktivität: Human
• Alternative Synonym: 1,4-cineole 2-exo-monooxygenase,1,8-cineole 2-exo-monooxygenase,Albendazole monooxygenase,albendazole monooxygenase (sulfoxide-forming),albendazole sulfoxidase,cholesterol 25-hydroxylase,CP33,CP34,CYP3A,CYP3A3,CYPIIIA3,CYPIIIA4,cytochrome P450 3A3,cytochrome P450 3A4,cytochrome P450 HLp,cytochrome P450 NF-25,cytochrome P450, family 3, subfamily A, polypeptide 4,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4,cytochrome P450-PCN1,glucocorticoid-inducible P450,HLP,NF-25,nifedipine oxidase,P450C3,P450-III, steroid inducible,P450PCN1,quinine 3-monooxygenase,taurochenodeoxycholate 6-alpha-hydroxylase,VDDR3.

Produktbeschreibung

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).

Produkteigenschaften

• Konzentration: 200 ug/mL (prior to lyoph)
• Molekulargewicht: 22kDa
• Tag: N-terminal His Tag
• NCBI: 1576
• Quelle: E.coli
• Reinheit: > 90%
• Formulierung: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.