CYP3A4 Recombinant Protein, E. coli

Product Overview

• Article Name: CYP3A4 Recombinant Protein, E. coli
• Biozol Catalog Number: ASB-OPCD02620
• Supplier Catalog Number: OPCD02620
• Alternative Catalog Number: ASB-OPCD02620-10UG, ASB-OPCD02620-200UG, ASB-OPCD02620-50UG
• Manufacturer: Aviva
• Host: E. coli
• Category: Proteine/Peptide
• Application: Control, WB
• Species Reactivity: Human
• Alternative Names: 1,4-cineole 2-exo-monooxygenase,1,8-cineole 2-exo-monooxygenase,Albendazole monooxygenase,albendazole monooxygenase (sulfoxide-forming),albendazole sulfoxidase,cholesterol 25-hydroxylase,CP33,CP34,CYP3A,CYP3A3,CYPIIIA3,CYPIIIA4,cytochrome P450 3A3,cytochrome P450 3A4,cytochrome P450 HLp,cytochrome P450 NF-25,cytochrome P450, family 3, subfamily A, polypeptide 4,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 3,cytochrome P450, subfamily IIIA (niphedipine oxidase), polypeptide 4,cytochrome P450-PCN1,glucocorticoid-inducible P450,HLP,NF-25,nifedipine oxidase,P450C3,P450-III, steroid inducible,P450PCN1,quinine 3-monooxygenase,taurochenodeoxycholate 6-alpha-hydroxylase,VDDR3.

Product Description

Cytochromes P450 are a group of heme-thiolate monooxygenases. In liver microsomes, this enzyme is involved in an NADPH-dependent electron transport pathway. It performs a variety of oxidation reactions (e.g. caffeine 8-oxidation, omeprazole sulphoxidation, midazolam 1-hydroxylation and midazolam 4-hydroxylation) of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. Acts as a 1,8-cineole 2-exo-monooxygenase. The enzyme also hydroxylates etoposide (PubMed:11159812). Catalyzes 4-beta-hydroxylation of cholesterol. May catalyze 25-hydroxylation of cholesterol in vitro (PubMed:21576599).

Product Properties

• Concentration: 200 ug/mL (prior to lyoph)
• Molecular Weight: 22kDa
• Tag: N-terminal His Tag
• NCBI: 1576
• Source: E.coli
• Purity: > 90%
• Form: Freeze-dried Powder. PBS, pH7.4, containing 0.01% SKL, 5% Trehalose.