NFKBIL2 antibody - middle region (P100874_P050), Rabbit, Polyclonal
Artikelnummer:
ASB-P100874_P050
Hersteller Artikelnummer:
P100874_P050
Alternativnummer:
ASB-P100874_P050-100UL, ASB-P100874_P050-25UL
Hersteller:
Aviva
Wirt:
Rabbit
Kategorie:
Antikörper
Applikation:
WB
Spezies Reaktivität:
Canine, Human, Mouse, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human NFKBIL2
Alternative Synonym:
IKBR, SEMDSP, NFKBIL2
NFKBIL2 is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
