NFKBIL2 antibody - middle region (P100874_P050), Rabbit, Polyclonal
Biozol Catalog Number:
ASB-P100874_P050
Supplier Catalog Number:
P100874_P050
Alternative Catalog Number:
ASB-P100874_P050-100UL, ASB-P100874_P050-25UL
Manufacturer:
Aviva
Host:
Rabbit
Category:
Antikörper
Application:
WB
Species Reactivity:
Canine, Human, Mouse, Rat
Immunogen:
The immunogen is a synthetic peptide directed towards the middle region of human NFKBIL2
Alternative Names:
IKBR, SEMDSP, NFKBIL2
NFKBIL2 is thought to be a negative regulator of NF-kappa-B mediated transcription. It may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.The protein encoded by this gene is thought to be a negative regulator of NF-kappa-B mediated transcription. The encoded protein may bind NF-kappa-B complexes and trap them in the cytoplasm, preventing them from entering the nucleus and interacting with the DNA. Phosphorylation of this protein targets it for degradation by the ubiquitination pathway, which frees the NF-kappa-B complexes to enter the nucleus.
