NFATC1 Antibody - N-terminal region

Artikelnummer: ASB-P100981_P050
Artikelname: NFATC1 Antibody - N-terminal region
Artikelnummer: ASB-P100981_P050
Hersteller Artikelnummer: P100981_P050
Alternativnummer: ASB-P100981_P050-25UL,ASB-P100981_P050-100UL
Hersteller: Aviva
Wirt: Rabbit
Kategorie: Proteine/Peptide
Applikation: IHC, WB
Spezies Reaktivität: Canine, Guinea pig, Human, Mouse
Immunogen: The immunogen is a synthetic peptide directed towards the N terminal region of human NFATC1
Alternative Synonym: NFAT2, NFATc, NF-ATC, NF-ATc1.2
NFATC1 is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Different isoforms of this protein may regulate inducible expression of different cytokine genes. The product of this gene is a component of the nuclear factor of activated T cells DNA-binding transcription complex. This complex consists of at least two components: a preexisting cytosolic component that translocates to the nucleus upon T cell receptor (TCR) stimulation, and an inducible nuclear component. Proteins belonging to this family of transcription factors play a central role in inducible gene transcription during immune response. The product of this gene is an inducible nuclear component. It functions as a major molecular target for the immunosuppressive drugs such as cyclosporin A. Five transcript variants encoding distinct isoforms have been identified for this gene. Different isoforms of this protein may regulate inducible expression of different cytokine genes.
Klonalität: Polyclonal
Konzentration: 0.5 mg/ml
Molekulargewicht: 78kDa
NCBI: 4772
Formulierung: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09% (w/v) sodium azide and 2% sucrose.
Rabbit Anti-NFATC1 Antibody
Catalog Number: P100981_P050
Formalin Fixed Paraffin Embedded Tissue: Human Adult liver
Observed Staining: Cytoplasmic in bile ducts and in sinusoids not in hepatocytes
Primary Antibody Concentration: 1:600
Secondary Antibody: Donkey anti-Rabbit-Cy2/3
Secondary Antibody Concentration: 1:200
Magnification: 20X
Exposure Time: 0.5 a€'' 2.0 sec
Protocol located in Reviews and Data.
WB Suggested Anti-NFATC1 Antibody Titration: 0.2-1 ug/ml
ELISA Titer: 1:312500
Positive Control: Human Stomach
WB Suggested Anti-NFATC1 antibody Titration: 1 ug/mL
Sample Type: Human liver
NFATC1 antibody - N-terminal region (P100981_P050) in Human Stomach using Western Blot