Mouse IL-38 Protein, His tag (Animal-Free)

Produktübersicht

• Artikelname: Mouse IL-38 Protein, His tag (Animal-Free)
• Artikelnummer: ASC-PRP1177
• Hersteller Artikelnummer: PRP1177
• Alternativnummer: ASC-PRP1177-5, ASC-PRP1177-20, ASC-PRP1177-100, ASC-PRP1177-1
• Hersteller: Abbkine Scientific
• Kategorie: Proteine/Peptide
• Alternative Synonym: interleukin 1 family, member 10, IL1F10

Produktbeschreibung

Interleukin 38 (IL-38) is a 16.87 kDa cytokine with 152 amino acid residues and a member of the interleukin-1 (IL-1) family. IL-38 is primarily secreted from basal epithelia of the skin and B cells of the tonsil, spleen, and thymus. It plays essential roles in inflammation and host defense by mediating NF-kappaB, AP1, and JNK signaling pathways when IL-38 binds to the receptors like IL1RAPL1 and IL-36R. In addition, IL-38 participates in down-regulating cell proliferation, migration, and up-regulating IL-6 and IL-10.

Produkteigenschaften

• Molekulargewicht: 17.89 kDa
• Tag: IL-38
• UniProt: Q8R459
• Reinheit: >98% as determined by SDS-PAGE.
• Formulierung: Lyophilized from PBS, pH 7.4
• Sequenz: Amino acid sequence derived from Mouse IL-38 (Met 1-Arg 152) (Q8R459) was expressed with 6*His tag at the C-terminus

Anwendungsbeschreibung

• Anwendungsbeschreibung: Mouse