Mouse IL-38 Protein, His tag (Animal-Free)

Product Overview

• Article Name: Mouse IL-38 Protein, His tag (Animal-Free)
• Biozol Catalog Number: ASC-PRP1177
• Supplier Catalog Number: PRP1177
• Alternative Catalog Number: ASC-PRP1177-5, ASC-PRP1177-20, ASC-PRP1177-100, ASC-PRP1177-1
• Manufacturer: Abbkine Scientific
• Category: Proteine/Peptide
• Alternative Names: interleukin 1 family, member 10, IL1F10

Product Description

Interleukin 38 (IL-38) is a 16.87 kDa cytokine with 152 amino acid residues and a member of the interleukin-1 (IL-1) family. IL-38 is primarily secreted from basal epithelia of the skin and B cells of the tonsil, spleen, and thymus. It plays essential roles in inflammation and host defense by mediating NF-kappaB, AP1, and JNK signaling pathways when IL-38 binds to the receptors like IL1RAPL1 and IL-36R. In addition, IL-38 participates in down-regulating cell proliferation, migration, and up-regulating IL-6 and IL-10.

Product Properties

• Molecular Weight: 17.89 kDa
• Tag: IL-38
• UniProt: Q8R459
• Purity: >98% as determined by SDS-PAGE.
• Form: Lyophilized from PBS, pH 7.4
• Sequence: Amino acid sequence derived from Mouse IL-38 (Met 1-Arg 152) (Q8R459) was expressed with 6*His tag at the C-terminus

Application Notes

• Application Notes: Mouse