CA19-9 (Sialyl Lewis A)(121SLE), 0.2mg/mL, Clone: [121SLE], Mouse, Monoclonal
Artikelnummer:
BOT-BNUB0025-100
Hersteller Artikelnummer:
BNUB0025-100
Alternativnummer:
BOT-BNUB0025-100-100UL
Hersteller:
Biotium
Wirt:
Mouse
Kategorie:
Antikörper
Applikation:
IHC
Spezies Reaktivität:
Human
Immunogen:
Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A B- patient (0Le).
Alternative Synonym:
CA19.9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a
CA19-9, a carbohydrate epitope expressed on a high MW (>400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains. It is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues. This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Klonalität:
Monoclonal
Konzentration:
0.2 mg/mL
Klon-Bezeichnung:
[121SLE]
Molekulargewicht:
>400 kDa
UniProt:
Not Known
Puffer:
PBS, 0.05% BSA, 0.05% azide
Quelle:
Animal
Anwendungsbeschreibung:
Immunohistology (formalin)|No special pretreatment is required for the immunohistochemical staining of formalin-fixed, paraffin-embedded tissues|Immunofluorescence 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL
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