CA19-9 (Sialyl Lewis A)(121SLE), 0.2mg/mL, Clone: [121SLE], Mouse, Monoclonal
Biozol Catalog Number:
BOT-BNUB0025-100
Supplier Catalog Number:
BNUB0025-100
Alternative Catalog Number:
BOT-BNUB0025-100-100UL
Manufacturer:
Biotium
Host:
Mouse
Category:
Antikörper
Application:
IHC
Species Reactivity:
Human
Immunogen:
Precipitin lines obtained after immuno-diffusion using MAb 116-NS-19-9 and mucins isolated from an ovarian cyst of a Lewis A B- patient (0Le).
Alternative Names:
CA19.9, Ovarian tumor antigen, Pancreatic tumor antigen, Sialyl Lewis a
CA19-9, a carbohydrate epitope expressed on a high MW (>400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains. It is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues. This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Clonality:
Monoclonal
Concentration:
0.2 mg/mL
Clone Designation:
[121SLE]
Molecular Weight:
>400 kDa
UniProt:
Not Known
Buffer:
PBS, 0.05% BSA, 0.05% azide
Source:
Animal
Application Notes:
Immunohistology (formalin)|No special pretreatment is required for the immunohistochemical staining of formalin-fixed, paraffin-embedded tissues|Immunofluorescence 0.5-1 ug/mL|Flow Cytometry 0.5-1 ug/million cells/0.1 mL
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