Melanoma Marker (MART-1 + gp100)(DT101+ BC199 + HMB45), 0.2mg/mL, Clone: [DT101 BC199 HMB45], Mouse, Monoclonal

Produktübersicht

• Artikelname: Melanoma Marker (MART-1 + gp100)(DT101+ BC199 + HMB45), 0.2mg/mL, Clone: [DT101 BC199 HMB45], Mouse, Monoclonal
• Artikelnummer: BOT-BNUB0703-500
• Hersteller Artikelnummer: BNUB0703-500
• Alternativnummer: BOT-BNUB0703-500-500UL
• Hersteller: Biotium
• Wirt: Mouse
• Kategorie: Antikörper
• Applikation: IHC
• Spezies Reaktivität: Human
• Immunogen: Recombinant hMART-1 protein (DT101 & BC199), Extract of pigmented melanoma metastases from lymph nodes (HMB45)
• Alternative Synonym: Melanoma antigen recognized by T-cells 1 (MART-1), MLAN-A, PMEL17

Produktbeschreibung

This antibody cocktail recognizes two melanoma-specific proteins, which include MART-1 and gp100. MART-1 is a newly identified melanocyte differentiation antigen recognized by autologous cytotoxic T lymphocytes. Function of gp100 is not known but it is reported to be a useful marker for melanocytes and melanomas. A cocktail of these two markers is sensitive for labeling formalin-fixed, paraffin-embedded melanomas and other tumors showing melanocytic differentiation.

Produkteigenschaften

• Klonalität: Monoclonal
• Konzentration: 0.2 mg/mL
• Klon-Bezeichnung: [DT101 BC199 HMB45]
• Molekulargewicht: 20-22 kDa (doublet) (MART-1), 90-100 kDa (gp100)
• UniProt: Q16655
• Puffer: PBS, 0.05% BSA, 0.05% azide
• Quelle: Animal

Anwendungsbeschreibung

• Anwendungsbeschreibung: Higher concentration may be required for direct detection using primary antibody conjugates than for indirect detection with secondary antibody|Immunohistochemistry (formalin-fixed): 0.5-1.0 ug/mL for 30 minutes at RT|Staining of formalin-fixed tissues is enhanced by boiling tissue sections in 10 mM citrate buffer pH 6.0 for 10-20 minutes followed by cooling at RT for 20 minutes|Optimal dilution for a specific application should be determined by user