Blood Group H Type 2 (CD173)(19-OLE), 0.2mg/mL, Clone: [19-OLE], Mouse, Monoclonal

Artikelnummer: BOT-BNUB0947-100
Artikelname: Blood Group H Type 2 (CD173)(19-OLE), 0.2mg/mL, Clone: [19-OLE], Mouse, Monoclonal
Artikelnummer: BOT-BNUB0947-100
Hersteller Artikelnummer: BNUB0947-100
Alternativnummer: BOT-BNUB0947-100-100UL
Hersteller: Biotium
Wirt: Mouse
Kategorie: Antikörper
Applikation: IHC
Spezies Reaktivität: Human
Immunogen: Mucinous colonic adenocarcinoma
Alternative Synonym: ABO Type O, Blood Group O, Blood Group H
This antibody is applicable for staining ABO blood group O. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. This antibody recognizes the blood group H type 2 antigens, trisaccharide Fuc-a-1-2Gal1-4GlcNAc-a-1. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.
Klonalität: Monoclonal
Konzentration: 0.2 mg/mL
Klon-Bezeichnung: [19-OLE]
Molekulargewicht: Multiple
UniProt: P16442
Puffer: PBS, 0.05% BSA, 0.05% azide
Quelle: Animal
Anwendungsbeschreibung: Immunohistology (formalin)|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes|Immunofluorescence 0.5-1 ug/mL|Optimal dilution for a specific application should be determined by user