Blood Group H Type 2 (CD173)(19-OLE), 0.2mg/mL, Clone: [19-OLE], Mouse, Monoclonal

Product Overview

• Article Name: Blood Group H Type 2 (CD173)(19-OLE), 0.2mg/mL, Clone: [19-OLE], Mouse, Monoclonal
• Biozol Catalog Number: BOT-BNUB0947-100
• Supplier Catalog Number: BNUB0947-100
• Alternative Catalog Number: BOT-BNUB0947-100-100UL
• Manufacturer: Biotium
• Host: Mouse
• Category: Antikörper
• Application: IHC
• Species Reactivity: Human
• Immunogen: Mucinous colonic adenocarcinoma
• Alternative Names: ABO Type O, Blood Group O, Blood Group H

Product Description

This antibody is applicable for staining ABO blood group O. The histo-blood group ABO involves three carbohydrate antigens: A, B, and H. This antibody recognizes the blood group H type 2 antigens, trisaccharide Fuc-a-1-2Gal1-4GlcNAc-a-1. A, B, and AB individuals express a glycosyltransferase activity that converts the H antigen to the A antigen (by addition of UDP-GalNAc) or to the B antigen (by addition of UDP-Gal), whereas O individuals lack such activity. It is expressed on endothelial cells, epithelial cells and granulocytes. Increased expression of this antigen has been observed on some tumor tissues such as gastric carcinomas, urothelial carcinomas, and colon carcinomas.This antibody is available purified with BSA/azide at 200 ug/mL, or BSA/azide-free at 1 mg/mL.

Product Properties

• Clonality: Monoclonal
• Concentration: 0.2 mg/mL
• Clone Designation: [19-OLE]
• Molecular Weight: Multiple
• UniProt: P16442
• Buffer: PBS, 0.05% BSA, 0.05% azide
• Source: Animal

Application Notes

• Application Notes: Immunohistology (formalin)|Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes|Immunofluorescence 0.5-1 ug/mL|Optimal dilution for a specific application should be determined by user