Langerin / CD207 (Marker of Langerhans Cells)(rLGRN/1821), 1mg/mL

Produktübersicht

• Artikelname: Langerin / CD207 (Marker of Langerhans Cells)(rLGRN/1821), 1mg/mL
• Artikelnummer: BOT-BNUM3608-50
• Hersteller Artikelnummer: BNUM3608-50
• Alternativnummer: BOT-BNUM3608-50-50UL
• Hersteller: Biotium
• Kategorie: Antikörper
• Spezies Reaktivität: Mouse

Produktbeschreibung

Langerhans cells (LCs) are a subset of immature dendritic cells (DCs) that specifically localize in the epidermis and other mucosal epithelia. Epidermal LCs possess strong immuno-stimulatory capacity and play a central role in the initiation and regulation of immune responses. Langerin (CD207) is a Ca2 -dependent, C-type lectin domain containing, type II transmembrane protein that induces epidermal LCs to differentiate into Birbeck granules (BG). BGs are organelles with superimposing and zippering membranes that influence proper class I type antigen presentation to the circulating T cells. Human spleen, lymph node, thymus, liver, lung and heart express Langerin protein. Primary antibodies are available purified, or with a selection of fluorescent CF Dyes and other labels. CF Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF405S and CF405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Produkteigenschaften

• Konzentration: 1 mg/mL
• Puffer: PBS, no BSA, no azide
• Quelle: Animal