GADD34 Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit

Produktübersicht

• Artikelname: GADD34 Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit
• Artikelnummer: BSS-BS-10287R-BF350
• Hersteller Artikelnummer: bs-10287R-BF350
• Alternativnummer: BSS-BS-10287R-BF350-100,BSS-BS-10287R-BF350-20
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: FC, IF, WB
• Spezies Reaktivität: Human
• Konjugation: BF350
• Alternative Synonym: GADD34, Protein phosphatase 1 regulatory subunit 15A, Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, PPP1R15A

Produktbeschreibung

Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on Ser-15.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 23645
• UniProt: O75807
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human GADD34
• Reinheit: Purified by Protein A.
• Target-Kategorie: GADD34

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)