GADD34 Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit

Product Overview

• Article Name: GADD34 Polyclonal Antibody, AbBy Fluor-350 Conjugated, BF350, Rabbit
• Biozol Catalog Number: BSS-BS-10287R-BF350
• Supplier Catalog Number: bs-10287R-BF350
• Alternative Catalog Number: BSS-BS-10287R-BF350-100,BSS-BS-10287R-BF350-20
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: FC, IF, WB
• Species Reactivity: Human
• Conjugation: BF350
• Alternative Names: GADD34, Protein phosphatase 1 regulatory subunit 15A, Growth arrest and DNA damage-inducible protein GADD34, Myeloid differentiation primary response protein MyD116 homolog, PPP1R15A

Product Description

Recruits the serine/threonine-protein phosphatase PP1 to dephosphorylate the translation initiation factor eIF-2A/EIF2S1, thereby reversing the shut-off of protein synthesis initiated by stress-inducible kinases and facilitating recovery of cells from stress. Down-regulates the TGF-beta signaling pathway by promoting dephosphorylation of TGFB1 by PP1. May promote apoptosis by inducing TP53 phosphorylation on Ser-15.

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 23645
• UniProt: O75807
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic peptide derived from human GADD34
• Purity: Purified by Protein A.
• Target: GADD34

Application Notes

• Application Dilute: WB(1:300-5000), FCM(1:20-100), IF(IHC-P)(1:50-200), IF(IHC-F)(1:50-200), IF(ICC)(1:50-200)