Phospho-HDAC4 (Ser246) Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: Phospho-HDAC4 (Ser246) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-10325R-BIOTIN
• Hersteller Artikelnummer: bs-10325R-Biotin
• Alternativnummer: BSS-BS-10325R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human
• Konjugation: Biotin
• Alternative Synonym: HDAC4Ser246, HDAC4S246, p-HDAC4Ser246, p-HDAC4S246, HD 4, HD4, HDAC 4, HDAC A, HDACA, Histone Deacetylase 4, Histone Deacetylase A, KIAA0288, EC 3.5.1.98, HA6116, HDA4_CAEEL, Histone deacetylase 4, CeHDA-7, Histone deacetylase 7.

Produktbeschreibung

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 9759
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser246
• Target-Kategorie: Phospho-HDAC4 (Ser246)

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)