Phospho-HDAC4 (Ser246) Polyclonal Antibody, Biotin Conjugated, Rabbit

Product Overview

• Article Name: Phospho-HDAC4 (Ser246) Polyclonal Antibody, Biotin Conjugated, Rabbit
• Biozol Catalog Number: BSS-BS-10325R-BIOTIN
• Supplier Catalog Number: bs-10325R-Biotin
• Alternative Catalog Number: BSS-BS-10325R-BIOTIN-100
• Manufacturer: Bioss
• Host: Rabbit
• Category: Antikörper
• Application: IHC-Fr, IHC-P, WB
• Species Reactivity: Human
• Conjugation: Biotin
• Alternative Names: HDAC4Ser246, HDAC4S246, p-HDAC4Ser246, p-HDAC4S246, HD 4, HD4, HDAC 4, HDAC A, HDACA, Histone Deacetylase 4, Histone Deacetylase A, KIAA0288, EC 3.5.1.98, HA6116, HDA4_CAEEL, Histone deacetylase 4, CeHDA-7, Histone deacetylase 7.

Product Description

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class II of the histone deacetylase/acuc/apha family. It possesses histone deacetylase activity and represses transcription when tethered to a promoter. This protein does not bind DNA directly, but through transcription factors MEF2C and MEF2D. It seems to interact in a multiprotein complex with RbAp48 and HDAC3. [provided by RefSeq, Jul 2008].

Product Properties

• Clonality: Polyclonal
• Concentration: 1ug/ul
• NCBI: 9759
• Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Source: KLH conjugated synthetic phosphopeptide derived from human HDAC4 around the phosphorylation site of Ser246
• Target: Phospho-HDAC4 (Ser246)

Application Notes

• Application Dilute: WB(1:300-5000), IHC-P(1:200-400), IHC-F(1:100-500)