CD33 Polyclonal Antibody, Biotin Conjugated, Rabbit

Artikelnummer: BSS-BS-2042R-BIOTIN-TRIAL
Artikelname: CD33 Polyclonal Antibody, Biotin Conjugated, Rabbit
Artikelnummer: BSS-BS-2042R-BIOTIN-TRIAL
Hersteller Artikelnummer: bs-2042R-Biotin
Alternativnummer: BSS-BS-2042R-BIOTIN-20
Hersteller: Bioss
Wirt: Rabbit
Kategorie: Antikörper
Applikation: ELISA, IHC-Fr, IHC-P, WB
Spezies Reaktivität: Human
Konjugation: Biotin
Alternative Synonym: p67, SIGLEC3, SIGLEC-3, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, gp67, CD33
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Klonalität: Polyclonal
Konzentration: 1ug/ul
NCBI: 945
UniProt: P20138
Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Quelle: KLH conjugated synthetic peptide derived from human CD33
Reinheit: Purified by Protein A.
Target-Kategorie: CD33
Antibody Type: Primary Antibody
Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)