CD33 Polyclonal Antibody, Biotin Conjugated, Rabbit

Catalog Number: BSS-BS-2042R-BIOTIN-TRIAL
Article Name: CD33 Polyclonal Antibody, Biotin Conjugated, Rabbit
Biozol Catalog Number: BSS-BS-2042R-BIOTIN-TRIAL
Supplier Catalog Number: bs-2042R-Biotin
Alternative Catalog Number: BSS-BS-2042R-BIOTIN-20
Manufacturer: Bioss
Host: Rabbit
Category: Antikörper
Application: ELISA, IHC-Fr, IHC-P, WB
Species Reactivity: Human
Conjugation: Biotin
Alternative Names: p67, SIGLEC3, SIGLEC-3, Myeloid cell surface antigen CD33, Sialic acid-binding Ig-like lectin 3, gp67, CD33
Putative adhesion molecule of myelomonocytic-derived cells that mediates sialic-acid dependent binding to cells. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. In the immune response, may act as an inhibitory receptor upon ligand induced tyrosine phosphorylation by recruiting cytoplasmic phosphatase(s) via their SH2 domain(s) that block signal transduction through dephosphorylation of signaling molecules. Induces apoptosis in acute myeloid leukemia (in vitro).
Clonality: Polyclonal
Concentration: 1ug/ul
NCBI: 945
UniProt: P20138
Buffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
Source: KLH conjugated synthetic peptide derived from human CD33
Purity: Purified by Protein A.
Target: CD33
Antibody Type: Primary Antibody
Application Dilute: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)