ALKBH5 Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: ALKBH5 Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-20540R-BIOTIN
• Hersteller Artikelnummer: bs-20540R-Biotin
• Alternativnummer: BSS-BS-20540R-BIOTIN-100
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P
• Spezies Reaktivität: Mouse, Rat
• Konjugation: Biotin
• Alternative Synonym: ABH5, AlkB, alkylation repair homolog 5 (E. coli), AlkB, alkylation repair homolog 5, Alkylated DNA repair protein alkB homolog 5, Alpha ketoglutarate dependent dioxygenase alkB homolog 5, OFOXD, OFOXD1, Oxoglutarate and iron-dependent oxygenase domain containing, Probable alpha ketoglutarate dependent dioxygenase ABH5, RNA demethylase ALKBH5.

Produktbeschreibung

Dioxygenase that demethylates RNA by oxidative demethylation: specifically demethylates N(6)-methyladenosine (m6A)RNA, the most prevalent internal modification of messenger RNA (mRNA) in higher eukaryotes (PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Can also demethylate N(6)-methyladenosine in single-stranded DNA (in vitro)(PubMed:24616105). Requires molecular oxygen, alpha-ketoglutarate and iron (PubMed:21264265, PubMed:23177736, PubMed:24778178,PubMed:24616105, PubMed:24489119). Demethylation of m6A mRNA affects mRNA processing and export (PubMed:23177736). Required for spermatogenesis (By similarity).

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 54890
• UniProt: Q6P6C2
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human ALKBH5
• Reinheit: Purified by Protein A.
• Target-Kategorie: ALKBH5
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)