OPG Polyclonal Antibody, Biotin Conjugated, Rabbit

Produktübersicht

• Artikelname: OPG Polyclonal Antibody, Biotin Conjugated, Rabbit
• Artikelnummer: BSS-BS-20624R-BIOTIN-TRIAL
• Hersteller Artikelnummer: bs-20624R-Biotin
• Alternativnummer: BSS-BS-20624R-BIOTIN-20
• Hersteller: Bioss
• Wirt: Rabbit
• Kategorie: Antikörper
• Applikation: ELISA, IHC-Fr, IHC-P, WB
• Spezies Reaktivität: Human, Mouse, Rat
• Konjugation: Biotin
• Alternative Synonym: Tumor necrosis factor receptor superfamily member 11B, TNFRSF11B, Osteoclastogenesis inhibitory factor, Osteoprotegerin, OCIF, OPG

Produktbeschreibung

Acts as decoy receptor for TNFSF11/RANKL and thereby neutralizes its function in osteoclastogenesis. Inhibits the activation of osteoclasts and promotes osteoclast apoptosis in vitro. Bone homeostasis seems to depend on the local ratio between TNFSF11 and TNFRSF11B. May also play a role in preventing arterial calcification. May act as decoy receptor for TNFSF10/TRAIL and protect against apoptosis. TNFSF10/TRAIL binding blocks the inhibition of osteoclastogenesis.

Produkteigenschaften

• Klonalität: Polyclonal
• Konzentration: 1ug/ul
• NCBI: 367
• UniProt: O00300
• Puffer: Aqueous buffered solution containing 0.01M TBS (pH 7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
• Quelle: KLH conjugated synthetic peptide derived from human OPG
• Reinheit: Purified by Protein A.
• Target-Kategorie: OPG
• Antibody Type: Primary Antibody

Anwendungsbeschreibung

• Application Verdünnung: WB(1:300-5000), ELISA(1:500-1000), IHC-P(1:200-400), IHC-F(1:100-500)